P-Glycoprotein (P-gp) Expressed in a Confluent Monolayer of hMDR1−MDCKII Cells Has More Than One Efflux Pathway with Cooperative Binding Sites-Reference-Cited by-同舟云学术

P-Glycoprotein (P-gp) Expressed in a Confluent Monolayer of hMDR1−MDCKII Cells Has More Than One Efflux Pathway with Cooperative Binding Sites

Published:2006-11-30 Issue:51 Volume:45 Page:15505-15519
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Acharya Poulomi¹,Tran Thuy T.¹,Polli Joseph W.¹,Ayrton Andrew¹,Ellens Harma¹,Bentz Joe¹

Affiliation:

1. Department of Bioscience and Biotechnology, Drexel University, Philadelphia, Pennsylvania 19104, Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Welwyn, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi060593b

Reference51 articles.

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. State-dependent inhibition of BK channels by the opioid agonist loperamide;Journal of General Physiology;2021-08-06

2. Case 8: Status of the of P-gp-Mediated Transport Through Confluent Cell Monolayers;Methods in Molecular Biology;2021

3. Simplified Method to Determine the Efflux Ratio on P-Glycoprotein Substrates Using Three-Compartment Model Analysis for Caco-2 Cell Assay Data;Pharmaceutical Research;2019-12-23

4. Involvement of human and canine MRP1 and MRP4 in benzylpenicillin transport;PLOS ONE;2019-11-27

5. A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics;Journal of Pharmaceutical Sciences;2017-09