Cobalt-Catalyzed Cyclotrimerization of Alkynes in Aqueous Solution

Author:

Sigman Matthew S.1,Fatland Anson W.1,Eaton Bruce E.1

Affiliation:

1. Department of Chemistry, Washington State University P.O. Box 644630, Pullman, Washington 99164-4630 NeXstar Pharmaceuticals, 2860 Wilderness Place Boulder, Colorado 80301

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference37 articles.

1. One-step synthesis of benzocyclobutenes involving cooligomerization of linear mono- and diacetylenes catalyzed by .eta.5-cyclopentadienylcobalt dicarbonyl

2. (b) Vollhardt, K. P. C.Angew. Chem., Int. Ed. Engl.1984,23, 539. For excellent reviews on metal-mediated cycloaddition, see:  (c) Grotjahn, D. B. InComprehensive Organometallic Chemistry II;Abel, E. W., Stone, F. G. A., Wilkinson, G., Hegedus, L. S., Eds.; Pergamon:  Tarrytown, NY, 1995; Vol. 12, pp 741−770.

3. Transition-metal-catalyzed alkyne cyclizations. A cobalt-mediated total synthesis of dl-estrone

4. Cobalt-mediated total synthesis of steroids. The A .fwdarw. BCD approach by enediyne cyclization

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