Novel Spirotetracyclic Zwitterionic Dual H1/5-HT2A Receptor Antagonists for the Treatment of Sleep Disorders-Reference-Cited by-同舟云学术

Novel Spirotetracyclic Zwitterionic Dual H1/5-HT2A Receptor Antagonists for the Treatment of Sleep Disorders

Published:2010-10-13 Issue:21 Volume:53 Page:7778-7795
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gianotti Massimo¹,Botta Maurizio²,Brough Stephen³,Carletti Renzo¹,Castiglioni Emiliano¹,Corti Corrado¹,Dal-Cin Michele¹,Delle Fratte Sonia¹,Korajac Denana⁴,Lovric Marija⁴,Merlo Giancarlo¹,Mesic Milan⁴,Pavone Francesca¹,Piccoli Laura¹,Rast Slavko⁴,Roscic Maja⁴,Sava Anna¹,Smehil Mario⁴,Stasi Luigi¹,Togninelli Andrea²,Wigglesworth Mark J.³

Affiliation:

1. Neurosciences CEDD, GlaxoSmithKline, Medicines Research Centre, Via A. Fleming 4, 37135 Verona, Italy

2. Dipartimento Farmaco Chimico Tecnologico, Universitá degli Studi di Siena, Via Aldo Moro 2, I-53100 Siena, Italy

3. GlaxoSmithKline, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, U.K.

4. Integrated Research Unit, IRU Chemistry, Prilaz Baruna Filipovica 29, 10000 Zagreb, Croatia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100856p

Reference36 articles.

1. National Sleep Foundation. Sleep in America Poll Highlight & Key Findings.http://www.sleepfoundation.org/, 2010.

2. Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time

3. Epidemiology of insomnia: what we know and what we still need to learn

4. Clinical Guideline for the Evaluation and Management of Chronic Insomnia in Adults

5. Sleep Disorders in the Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR,4th ed.American Psychiatric Association:Arlington, VA, 2000; pp597−661.

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