Cationic Amphiphilic Drugs Cause a Marked Expansion of Apparent Lysosomal Volume: Implications for an Intracellular Distribution-Based Drug Interaction-Reference-Cited by-同舟云学术

Cationic Amphiphilic Drugs Cause a Marked Expansion of Apparent Lysosomal Volume: Implications for an Intracellular Distribution-Based Drug Interaction

Published:2012-04-06 Issue:5 Volume:9 Page:1384-1395
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Funk Ryan S.¹,Krise Jeffrey P.¹

Affiliation:

1. Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp200641e

Reference58 articles.

1. Lysosomotropic agents

2. Effects of exogenous amines on mammalian cells, with particular reference to membrane flow

3. Human accumulation potential of xenobiotics: potential of catamphiphilic drugs to promote their accumulation via inducing lipidosis or mucopolysaccharidosis

4. Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

5. Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

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