SAR Studies on Curcumin’s Pro-inflammatory Targets: Discovery of Prenylated Pyrazolocurcuminoids as Potent and Selective Novel Inhibitors of 5-Lipoxygenase-Reference-Cited by-同舟云学术

SAR Studies on Curcumin’s Pro-inflammatory Targets: Discovery of Prenylated Pyrazolocurcuminoids as Potent and Selective Novel Inhibitors of 5-Lipoxygenase

Published:2014-06-24 Issue:13 Volume:57 Page:5638-5648
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Koeberle Andreas¹,Muñoz Eduardo²,Appendino Giovanni B.³,Minassi Alberto³,Pace Simona¹⁴,Rossi Antonietta⁴,Weinigel Christina⁵,Barz Dagmar⁵,Sautebin Lidia⁴,Caprioglio Diego³,Collado Juan A.²,Werz Oliver¹

Affiliation:

1. Chair of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, University Jena, Philosophenweg 14, 07743 Jena, Germany

2. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofía, Universidad de Córdoba, Avda Menendez Pidal s/n, 14004 Córdoba, Spain

3. Dipartimento di Scienze del Farmaco, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy

4. Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 46, 80131 Naples, Italy

5. Institute of Transfusion Medicine, University Hospital Jena, Bachstrasse 18, 07743 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500308c

Reference56 articles.

1. Curcumin, a component of turmeric: From farm to pharmacy

2. Curcumin: From ancient medicine to current clinical trials

3. Comparative Absorption of a Standardized Curcuminoid Mixture and Its Lecithin Formulation