An Oxazole-Based Small-Molecule Stat3 Inhibitor Modulates Stat3 Stability and Processing and Induces Antitumor Cell Effects

Author:

Siddiquee Khandaker A. Z.12,Gunning Patrick T.3,Glenn Matthew3,Katt William P.3,Zhang Shumin4,Schroeck Christopher4,Sebti Said M.567,Jove Richard89,Hamilton Andrew D.3,Turkson James12

Affiliation:

1. BioMolecular Science Center and

2. Department of Molecular Biology and Microbiology, University of Central Florida College of Medicine, Orlando, Florida 32826

3. Department of Chemistry, Yale University, New Haven, Connecticut 06520

4. Molecular Oncology and

5. Drug Discovery Programs, H. Lee Moffitt Cancer Center and Research Institute and Departments of

6. Interdisciplinary Oncology

7. Biochemistry and Molecular Biology, University of South Florida College of Medicine, Tampa, Florida 33612

8. Developmental Cancer Therapeutics Program, City of Hope Comprehensive Cancer Center, City of Hope, Duarte, California 91010

9. Division of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California 91010

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

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