High Affinity Interaction between a Synthetic, Highly Negatively Charged Pentasaccharide and α- or β-Antithrombin Is Predominantly Due to Nonionic Interactions

Author:

Hjelm Rebecka1,Schedin-Weiss Sophia1

Affiliation:

1. Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala Biomedical Center, Box 582, SE-751 23 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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3. Heparin/heparan sulphate-based drugs;Drug Discovery Today;2010-12

4. Anticoagulants;Burger's Medicinal Chemistry and Drug Discovery;2010-09-15

5. Glycosaminoglycans as polyelectrolytes;Advances in Colloid and Interface Science;2010-07

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