Practical Synthesis of 5-Fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a Key Intermediate in the Preparation of Potent Deoxycytidine Kinase Inhibitors

Author:

Zhang Haiming1,Yan Jie1,Kanamarlapudi Ramanaiah C.1,Wu Wenxue1,Keyes Philip1

Affiliation:

1. Chemical Development, Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey 08540, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Telescope Approach;Handbook for Chemical Process Research and Development;2016-10-17

2. Protection for the Amino Group;Greene's Protective Groups in Organic Synthesis;2014-08-11

3. Fluorine Containing Diazines. Synthesis and Properties;Fluorine in Heterocyclic Chemistry Volume 2;2014

4. Structural characterization, recognition patterns and theoretical calculations of long-chain N-alkyl substituted purine and pyrimidine bases as ligands: On the importance of anion–π interactions;Coordination Chemistry Reviews;2013-10

5. One-pot Synthesis and its Practical Application in Pharmaceutical Industry;Current Organic Synthesis;2012-11-01

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