Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

Author:

Peifer Christian1,Stoiber Thomas1,Unger Eberhard1,Totzke Frank1,Schächtele Christoph1,Marmé Dieter1,Brenk Ruth1,Klebe Gerhard1,Schollmeyer Dieter1,Dannhardt Gerd1

Affiliation:

1. Department of Pharmacy, Johannes Gutenberg-University, Staudingerweg 5, D-55099 Mainz, Germany, Department of Single Cell and Single Molecule Techniques, Institute of Molecular Biotechnology, Beutenbergstraβe 11, D-07745 Jena, Germany, ProQinase GmbH, Breisacherstrasse 117, D-79106 Freiburg, Germany, Department of Pharmacy, Philipps-University, Marbacherweg 6, D-35032 Marburg, Germany, and Department of Organic Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, D-55099 Mainz, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference53 articles.

1. Angiogenesis in cancer and other diseases

2. Fan, T. D.; Brem, S. InAngiosuppression. The search for new anti-cancerdrugs; Waring, M. J., Ponder, B., Eds.; Kluwer Academic Press: Dordrecht, The Netherlands, 1992; pp 185−229.

3. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle

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