1. Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan, Faculty of Medical Engineering, Suzuka University of Medical Science, 1001-1 Kishioka-cho, Suzuka 510-0293, Japan, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan, and Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation