Design and Optimization of 20-O-Linked Camptothecin Glycoconjugates as Anticancer Agents
Author:
Affiliation:
1. Bayer AG, Central Research, Life Sciences, 51368 Leverkusen, Germany, Bayer AG, Pharma Research Center, 42096 Wuppertal, Germany, and Institute for Experimental Oncology, Oncotest GmbH, 79108 Freiburg, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm010893l
Reference19 articles.
1. Bifunctional Reagents. Cross-Linking of Pancreatic Ribonuclease with a Diimido Ester1
2. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity
3. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
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