Design, Synthesis, and Biological Evaluation of 2,4-Diamino-5-methyl-6-substituted-pyrrolo[2,3-d]pyrimidines as Dihydrofolate Reductase Inhibitors-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of 2,4-Diamino-5-methyl-6-substituted-pyrrolo[2,3-d]pyrimidines as Dihydrofolate Reductase Inhibitors

Published:2004-05-08 Issue:14 Volume:47 Page:3689-3692
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gangjee Aleem¹,Lin Xin¹,Queener Sherry F.¹

Affiliation:

1. Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, 600 Forbes Avenue, Duquesne University, Pittsburgh, Pennsylvania 15282, and Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, Indiana 46202

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0306327

Reference14 articles.

1. Presented in part at the 218th National Meeting of the American Chemical Society, New Orleans, LA, August 22−26, 1999; MEDI-224.

2. Drug Treatment of HIV-Related Opportunistic Infections

3. The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 å resolution

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