Synthesis and Biological Evaluation of New Creatine Fatty Esters Revealed Dodecyl Creatine Ester as a Promising Drug Candidate for the Treatment of the Creatine Transporter Deficiency-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of New Creatine Fatty Esters Revealed Dodecyl Creatine Ester as a Promising Drug Candidate for the Treatment of the Creatine Transporter Deficiency

Published:2013-06-07 Issue:12 Volume:56 Page:5173-5181
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Trotier-Faurion Alexandra¹,Dézard Sophie²,Taran Frédéric²,Valayannopoulos Vassili³,de Lonlay Pascale³,Mabondzo Aloïse¹

Affiliation:

1. CEA, DSV, iBiTec-S, Service de Pharmacologie et d’Immunoanalyse, 91191 Gif sur Yvette, France

2. CEA, DSV, iBiTec-S, Service de Chimie Bio Organique et de Marquage, Gif sur Yvette, France

3. Centre de Référence des Maladies Héréditaires du Métabolisme de l′Enfant et de l′Adulte, Hôpital Necker-Enfants Malades, Université Paris Descartes, Paris, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400545n

Reference25 articles.

1. Cerebral Creatine Deficiency Syndromes: Clinical Aspects, Treatment and Pathophysiology

2. Creatine and Creatinine Metabolism

3. Creatine replacement therapy in guanidineoacetate methyltransferase deficiency, a novel inborn error of metabolism

4. X-Linked creatine transporter deficiency in two patients with severe mental retardation and autism

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