Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness-Reference-Cited by-同舟云学术

Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness

Published:2014-05-21 Issue:11 Volume:57 Page:4834-4848
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Seixas João D.¹²,Luengo-Arratta Sandra A.¹²,Diaz Rosario²,Saldivia Manuel²,Rojas-Barros Domingo I.²,Manzano Pilar³,Gonzalez Silvia³,Berlanga Manuela³,Smith Terry K.⁴,Navarro Miguel²,Pollastri Michael P.¹

Affiliation:

1. Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States

2. Instituto de Parasitología y Biomedicina “López-Neyra”, Granada 18100, Spain

3. Tres Cantos Medicines Development Campus, DDW and CIB, GlaxoSmithKline, 28760 Tres Cantos, Spain

4. Biomedical Sciences Research Complex, University of St Andrews, North Haugh, St Andrews, Fife, KY16 9ST, United Kingdom

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500361r

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5. Tyrosine Kinases and Inflammatory Signalling

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