1. Department of Nursing, Chang Jung Christian University, No. 396, Sec. 1, Changrong Road, Gueiren, Tainan 711, Taiwan, Department of Microbiology and Immunology, Medical College, National Cheng Kung University, No. 1, Ta-Hsueh Road, Tainan 701, Taiwan, and School of Pharmacy, Kaohsiung Medical University, No. 100, Shih-Chuan first Road, Kaohsiung 807, Taiwan