Identification by NMR Spectroscopy of the Two Stereoisomers of the Platinum Complex [PtCl2(S-ahaz)] (S-ahaz = 3(S)-Aminohexahydroazepine) Bound to a DNA 14-mer Oligonucleotide. NMR Evidence of Structural Alteration of a Platinated A·T-rich 14-mer DNA Duplex-Reference-Cited by-同舟云学术

Identification by NMR Spectroscopy of the Two Stereoisomers of the Platinum Complex [PtCl2(S-ahaz)] (S-ahaz = 3(S)-Aminohexahydroazepine) Bound to a DNA 14-mer Oligonucleotide. NMR Evidence of Structural Alteration of a Platinated A·T-rich 14-mer DNA Duplex

Published:2009-03-05 Issue:7 Volume:48 Page:3047-3056
ISSN:0020-1669
Container-title:Inorganic Chemistry
language:en
Short-container-title:Inorg. Chem.

Author:

Diakos Connie I.¹,Messerle Barbara A.¹,del Socorro Murdoch P.¹,Parkinson John A.¹,Sadler Peter J.¹,Fenton Ronald R.¹,Hambley Trevor W.¹

Affiliation:

1. School of Chemistry, University of Sydney, NSW 2006, Australia, School of Chemical Sciences, University of New South Wales, NSW 2052, Australia, Department of Chemistry, University of Edinburgh, King’s Buildings, West Mains Road, Edinburgh EH9 3JJ, U.K., Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K. and WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 16 Richmond Street, Glasgow, U.K.

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ic802207m

Reference39 articles.

1. The resurgence of platinum-based cancer chemotherapy

2. RNA polymerases react differently at d(ApG) and d(GpG) adducts in DNA modified by cis-diamminedichloroplatinum(II)

3. Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II)

4. Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy.

5. Replication inhibition and translesion synthesis on templates containing site- specifically placed cis-diamminedichloroplatinum(II) DNA adducts

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