1. Department of Pharmacology, Xin Hua University of Anhui, Hefei 230088, Anhui, China
2. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, Anhui, China
3. Department of Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui, China
4. Bristol-Myers Squibb, Lawrenceville, New Jersey 08648, United States