Metformin Hydrochloride Encapsulation by Alginate Strontium Hydrogel for Cartilage Regeneration by Reliving Cellular Senescence

Author:

Xu Lei1234,Ma Fenbo1,Huang Jun1,Frankie Leung Ka Li2,Qin Chenghe4,Lu William Weijia2,Guo X. Edward3,Tang Bin156ORCID

Affiliation:

1. Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen 518055, Guangdong, People’s Republic of China

2. Department of Orthopeadics and Traumatology, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, SAR, People’s Republic of China

3. Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, 10027 New York, United States

4. Department of Orthopeadics and Traumatology, Guangdong Second Provincial General Hospital, Guangzhou 510317, Guang Dong, People’s Republic of China

5. Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, SUSTech, Schenzhen, Guangdong, People’s Republic of China

6. Shenzhen Key Laboratory of Cell Microenvironment, SUSTech, Schenzhen, Guangdong, People’s Republic of China

Funder

Ministry of Science and Technology of the People's Republic of China

Science, Technology and Innovation Commission of Shenzhen Municipality

National Natural Science Foundation of China

Guangdong Foundation of Science and Technology

Special Fund for the Cultivation of Science and Technology Innovation for Guangdong University Students

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

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