Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers-Reference-Cited by-同舟云学术

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

Published:2020-02-03 Issue:3 Volume:21 Page:1112-1125
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Ghadami Seyyed Abolghasem¹,Chia Sean²,Ruggeri Francesco Simone²,Meisl Georg²^ORCID,Bemporad Francesco¹,Habchi Johnny²,Cascella Roberta¹,Dobson Christopher M.²,Vendruscolo Michele²^ORCID,Knowles Tuomas P. J.²³^ORCID,Chiti Fabrizio¹^ORCID

Affiliation:

1. Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, Section of Biochemistry, University of Florence, 50134 Florence, Italy

2. Department of Chemistry, Centre for Misfolding Diseases, University of Cambridge, Cambridge CB2 1EW, U.K.

3. Department of Physics, Cavendish Laboratory, 19 J. J. Thomson Avenue, Cambridge CB3 0HE, U.K.

Funder

Darwin College, University of Cambridge

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Ministry of Science Research and Technology

Universit? degli Studi di Firenze

Centre for Misfolding Diseases, University of Cambridge

Department of Chemistry, University of Cambridge

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.biomac.9b01475

Reference64 articles.

1. An english translation of alzheimer's 1907 paper, ?�ber eine eigenartige erkankung der hirnrinde?

2. The amyloid hypothesis of Alzheimer's disease at 25 years

3. Transthyretin sequesters amyloid beta protein and prevents amyloid formation.

4. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A toxicity

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