Poly(lactide-co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung Infection: in Vitro and in Vivo Studies

Author:

Casciaro Bruno12,d’Angelo Ivana3,Zhang Xiaoping4,Loffredo Maria Rosa1,Conte Gemma35,Cappiello Floriana1,Quaglia Fabiana5ORCID,Di Yuan-Pu Peter4,Ungaro Francesca5,Mangoni Maria Luisa1ORCID

Affiliation:

1. Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, via degli Apuli, 9, 00185 Rome, Italy

2. Center for Life Nano Science, Istituto Italiano di Tecnologia, 00161 Rome, Italy

3. Di.S.T.A.Bi.F., University of Campania “Luigi Vanvitelli”, Via Vivaldi 43, 81100 Caserta, Italy

4. Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

5. Department of Pharmacy, University of Naples Federico II, Via D Montesano 49, 80131 Naples, Italy

Funder

Sapienza Universit?? di Roma

Cystic Fibrosis Foundation

U.S. Department of Health and Human Services

Istituto Pasteur-Fondazione Cenci Bolognetti

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

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