Development and In Vitro/Ex Vivo Characterization of Vaginal Mucoadhesive Bilayer Films Based on Ethylcellulose and Biopolymers for Vaginal Sustained Release of Tenofovir-Reference-Cited by-同舟云学术

Development and In Vitro/Ex Vivo Characterization of Vaginal Mucoadhesive Bilayer Films Based on Ethylcellulose and Biopolymers for Vaginal Sustained Release of Tenofovir

Published:2020-04-08 Issue:6 Volume:21 Page:2309-2319
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Cazorla-Luna Raúl¹,Notario-Pérez Fernando¹,Martín-Illana Araceli¹,Bedoya Luis-Miguel²^ORCID,Tamayo Aitana³,Rubio Juan³,Ruiz-Caro Roberto¹,Veiga María-Dolores¹^ORCID

Affiliation:

1. Departamento de Farmacia Galénica y Tecnologı́a Alimentaria, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain

2. Departamento Farmacologı́a, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain

3. Departamento de Quı́mica-Fı́sica de Superficies y Procesos, Instituto de Cerámica y Vidrio (ICV), Consejo Superior de Investigaciones Cientı́ficas (CSIC), 28049 Madrid, Spain

Funder

Ministry of Science, Innovation and Universities

European Commission

Agencia Estatal de Investigaci??n

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biomac.0c00249

Reference55 articles.

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2. Overview of microbicides for the prevention of human immunodeficiency virus

3. United Nations Joint Programme on HIV/AIDS (UNAIDS). HVTN 702 Clinical Trial of an HIV Vaccine Stopped. https://www.unaids.org/en/resources/presscentre/pressreleaseandstatementarchive/2020/february/20200204_vaccine (accessed Apr 6, 2020).

4. MTN-001: Randomized Pharmacokinetic Cross-Over Study Comparing Tenofovir Vaginal Gel and Oral Tablets in Vaginal Tissue and Other Compartments

5. Influence of Chitosan Swelling Behaviour on Controlled Release of Tenofovir from Mucoadhesive Vaginal Systems for Prevention of Sexual Transmission of HIV

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