Minor Structural Modifications Convert the Dual TP/CRTH2 Antagonist Ramatroban into a Highly Selective and Potent CRTH2 Antagonist
Author:
Affiliation:
1. 7TM Pharma A/S, Fremtidsvej 3, DK-2970 Hørsholm, Denmark
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm049036i
Reference34 articles.
1. Increased Production of Prostaglandin D2 in Patients with Systemic Mastocytosis
2. Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene.
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