Selective Lewis Acid Catalyzed Assembly of Phosphonomethyl Ethers: Three-Step Synthesis of Tenofovir
Author:
Affiliation:
1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
Funder
Bill and Melinda Gates Foundation
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol503612h
Reference19 articles.
1. World Health Organization. HIV/AIDS. http://www.who.int/hiv/en/(accessed Oct 14, 2014) .
2. aBill and Melinda Gates Foundation. HIVStrategy Overview. http://www.gatesfoundation.org/What-We-Do/Global-Health/HIV(accessed Nov 10, 2014) .
3. bClinton Health Access Initiative. HIV/AIDS.http://www.clintonhealthaccess.org/program-areas/HIV-AIDS(accessed Nov 10, 2014) .
4. Antiretroviral Efficacy and Pharmacokinetics of Oral Bis(isopropyloxycarbonyloxymethyl)9-(2-Phosphonylmethoxypropyl)adenine in Mice
5. Anti-Human Immunodeficiency Virus Activity and Cellular Metabolism of a Potential Prodrug of the Acyclic Nucleoside Phosphonate 9- R -(2-Phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA
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