Direct and Simple O-Demethylation of Thebaine to Oripavine
Author:
Affiliation:
1. Laboratory of Medicinal Chemistry, National Institute of Diabetes, Digestive and Kidney Diseases, Building 8, Room B1-23, Bethesda, Maryland 20892-0815, and School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo961473k
Reference13 articles.
1. Casy, A. F.; Parfitt, R. T.Opioid Analgesics; Plenum Press: New York and London, 1986.
2. Casy, A. F.The Steric Factor in Medicinal Chemistry; Plenum Press: New York and London,1993; pp 429−465.
3. Synthesis of thebaine and oripavine from codeine and morphine
4. O-Demethylation of Opioid Derivatives with Methane Sulfonic Acid/ Methionine: Application to the Synthesis of Naloxone and Analogues
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