Determination of Drug−Plasma Protein Binding Kinetics and Equilibria by Chromatographic Profiling: Exemplification of the Method Using l-Tryptophan and Albumin-Reference-Cited by-同舟云学术

Determination of Drug−Plasma Protein Binding Kinetics and Equilibria by Chromatographic Profiling: Exemplification of the Method Using l-Tryptophan and Albumin

Published:2001-12-12 Issue:2 Volume:74 Page:446-452
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Talbert Ann M.¹,Tranter George E.¹,Holmes Elaine¹,Francis Peter L.¹

Affiliation:

1. Biological Chemistry, Biomedical Sciences Division, Imperial College of Science, Technology and Medicine, Exhibition Road, London SW7 2AZ, U.K., and Glaxo Smith Kline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac010643c

Reference30 articles.

1. Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs

2. Benet, L. Z.; Kroetz, D. L.; Sheiner, L. B. InGoodman and Gilman's ThePharmacological Basis of Therapeutics, 9th ed.; Hardman, J. G., Gilman, A. G., Limbird, L. E., Eds.; McGraw-Hill: New York, 1996; p 10.

3. Human Serum Albumin as a ‘Silent Receptor’ for Drugs and Endogenous Substances

4. Drug Binding in Plasma

5. Guyton, A. C.Textbook of Medical Physiology, 9th ed.; W.B Saunders: Philadelphia, 1996; pp 161−164.

Cited by 94 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Moment Analysis Method for Measurement of Reaction Equilibrium and Rate Constants by Using High-Performance Liquid Chromatography;Analytical Chemistry;2024-03-08

2. Thermodynamic insight into the interaction mechanism of an ESIPT drug with a serum transport protein: Slower solvent-relaxation dynamics explored through wavelength-sensitive fluorescence behavior;Chemical Physics Impact;2023-06

3. Immobilization of M3 Muscarinic Receptor to Rapidly Analyze Drug—Protein Interactions and Bioactive Components in a Natural Plant;International Journal of Molecular Sciences;2023-04-12

4. New Methodology for Determining Plasma Protein Binding Kinetics Using an Enzyme Reporter Assay Coupling with High-Resolution Mass Spectrometry;Analytical Chemistry;2023-02-15

5. Affinity chromatography;Liquid Chromatography;2023