Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors-Reference-Cited by-同舟云学术

Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors

Published:2014-09-30 Issue:19 Volume:57 Page:8026-8034
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tang Guozhi¹,Wong Jason C.¹,Zhang Weixing¹,Wang Zhanguo¹,Zhang Nan¹,Peng Zhenghong¹,Zhang Zhenshan¹,Rong Yiping¹,Li Shijie¹,Zhang Meifang¹,Yu Lingjie¹,Feng Teng¹,Zhang Xiongwen¹,Wu Xihan¹,Wu Jim Z.¹,Chen Li¹

Affiliation:

1. Roche Pharmaceutical Research and Early Development, Roche Innovation Center Shanghai, 720 Cailun Road, Shanghai, 201203 China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5008962

Reference28 articles.

1. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

2. Therapeutic potential of isoform selective HDAC inhibitors for the treatment of schizophrenia

3. Isoform-selective HDAC inhibitors: Closing in on translational medicine for the heart

4. Structural Biasing Elements for In-Cell Histone Deacetylase Paralog Selectivity

5. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

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