The Identification of the 2-Phenylphthalazin-1(2H)-one Scaffold as a New Decorable Core Skeleton for the Design of Potent and Selective Human A3 Adenosine Receptor Antagonists-Reference-Cited by-同舟云学术

The Identification of the 2-Phenylphthalazin-1(2H)-one Scaffold as a New Decorable Core Skeleton for the Design of Potent and Selective Human A3 Adenosine Receptor Antagonists

Published:2011-03-14 Issue:7 Volume:54 Page:2102-2113
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Poli Daniela¹,Catarzi Daniela¹,Colotta Vittoria¹,Varano Flavia¹,Filacchioni Guido¹,Daniele Simona²,Trincavelli Letizia²,Martini Claudia²,Paoletta Silvia³,Moro Stefano³

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Firenze, Polo Scientifico, Via U. Schiff, 6-50019 Sesto Fiorentino (Firenze), Italy

2. Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università degli Studi di Pisa, Via Bonanno, 6-50126 Pisa, Italy

3. Molecular Modeling Section (MMS), Dipartimento di Scienze Farmaceutiche, Università degli Studi di Padova, via Marzolo 5, I-35131 Padova, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101328n

Reference49 articles.

1. P1 and P2 Purine and Pyrimidine Receptor Ligands

2. Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury

3. Signalling from adenosine receptors to mitogen-activated protein kinases

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