Synthesis of Nitrogen Analogues of Salacinol and Their Evaluation as Glycosidase Inhibitors

Author:

Ghavami Ahmad1,Johnston Blair D.1,Jensen Morten T.1,Svensson Birte1,Pinto B. Mario1

Affiliation:

1. Contribution from the Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6, and Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Copenhagen, Denmark

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference28 articles.

1. For example:  Garcia-Olmeda, F.; Salcedo, G.; Sanchez-Monge, R.; Gomez, L.; Royo, L.; Carbonero, P.Oxford Surveys of Plant Molecular andCell Biology; Clarendon Press:  Oxford, 1987; Vol. 4, pp 275−334; Vertesy, L.; Oeding, V.; Bender, R.; Zepf, K.; Nesemann, G.Eur. J. Biochem.1984,141, 505−512; Vallée, F.; Kadziola, A.; Bourne, Y.; Juy, M.; Rodenburg, K. W.; Svensson, B.; Haser, R.Structure1998,6, 649−659; Bompard-Gilles, C.; Rousseau, P.; Rougé, P.; Payan, F.Structure1996,4, 1441−1452; Strobl, S.; Maskos, K.; Wiegand, G.; Huber, R.; Gomis-Rüth, F.X.; Glockshuber, R.Structure1998,6, 911−921.

2. A randomized double-blind trial of acarbose in type 2 diabetes shows improved glycemic control over 3 years (U.K. Prospective Diabetes Study 44)

3. Glycosylation inhibitors in biology and medicine

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