Inhibition of Trypanosoma cruzi Trypanothione Reductase by Acridines: Kinetic Studies and Structure−Activity Relationships
Author:
Affiliation:
1. Biochemie-Zentrum Heidelberg, Heidelberg University, Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany, and GERCTOP-UPRESA CNRS 6009, Faculté de Pharmacie, Université de la Mediterrannée, 27 Bd Jean-Moulin, F-13385 Marseille, France
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm990386s
Reference46 articles.
1. METABOLISM AND FUNCTIONS OF TRYPANOTHIONE IN THE KINETOPLASTIDA
2. Evidence for the co-existence of glutathione reductase and trypanothione reductase in the non-trypanosomatid Euglenozoa: Euglena gracilis Z
3. Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids
4. Active site of trypanothione reductase
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