OMP Decarboxylase: Phosphodianion Binding Energy Is Used To Stabilize a Vinyl Carbanion Intermediate
Author:
Affiliation:
1. Department of Chemistry, University at Buffalo, Buffalo, New York 14260, United States
2. Departments of Biochemistry and Chemistry, University of Illinois, Urbana, Illinois 61801, United States
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja201734z
Reference17 articles.
1. OMP decarboxylase—An enigma persists
2. Catalytic Proficiency: The Unusual Case of OMP Decarboxylase
3. A Proficient Enzyme
4. Formation and Stability of a Vinyl Carbanion at the Active Site of Orotidine 5‘-Monophosphate Decarboxylase: pKa of the C-6 Proton of Enzyme-Bound UMP
5. Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Evidence for Substrate Destabilization,
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