6-Substituted Benzopyrans as Potassium Channel Activators: Synthesis, Vasodilator Properties, and Multivariate Analysis-Reference-Cited by-同舟云学术

6-Substituted Benzopyrans as Potassium Channel Activators: Synthesis, Vasodilator Properties, and Multivariate Analysis

Published:1999-03-01 Issue:6 Volume:42 Page:981-991
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mannhold Raimund¹,Cruciani Gabriele¹,Weber Horst¹,Lemoine Horst¹,Derix Andrea¹,Weichel Claus¹,Clementi Monica¹

Affiliation:

1. Institut für Lasermedizin, Arbeitsgruppe Molekulare Wirkstoff-Forschung, and Institut für Pharmazeutische Chemie, Heinrich-Heine-Universität, Universitätsstrasse 1, D-40225 Düsseldorf, Germany, and Dipartimento di Chimica, Laboratorio di Chemiometria, Università di Perugia, Via Elce di Sotto, 8, I-06123 Perugia, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm981047m

Reference25 articles.

1. Recent advances in the understanding of potassium channel function

2. A superfamily of ion channels

3. ATP-regulated K+ channels in cardiac muscle

4. The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying K+ channel Kir6.1 expressed in human embryonic kidney cells.

5. Structure-activity relationships of K+ channel openers

Cited by 57 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 2,2-Dimethylbenzopyrans;Privileged Structures in Drug Discovery;2018-03-09

2. Polarity study of ionic liquids with the solvatochromic dye Nile Red: a QSPR approach using in silico VolSurf+ descriptors;Tetrahedron;2016-06

3. Modelling the aquatic toxicity of ionic liquids by means of VolSurfin silicodescriptors;SAR and QSAR in Environmental Research;2016-01-02

4. Efficient One-Pot Synthesis of 2,2-Dimethyl-2H-chromenes via Pd(II)-Catalyzed Coupling and SiO2-Promoted Condensation of o-Halophenols with 2-Methyl-3-buten-2-ol;Synthetic Communications;2015-07-20

5. Synthesis, Characterization, and Antihypertensive Evaluation of Some Novel 2,2,8,8-Tetramethyl-2,3,7,8-tetrahydro-4,6-diamino-3,7-dihydroxy-6,7-epoxy-benzo-[1,2-b:5,4-b′]dipyran Derivatives;Advances in Chemistry;2015-01-29