1. Department of Pharmaceutical Sciences, University of Bologna, via Belmeloro 6, 40126 Bologna, Italy, and Department of Internal Medicine and Gastroenterology, University of Bologna, via Massarenti 9, 40138 Bologna, Italy, and Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, Campo Boario, 64100 Teramo, Italy