Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation-Reference-Cited by-同舟云学术

Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation

Published:2019-02-25 Issue:12 Volume:141 Page:4849-4860
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Khatri Hem Raj¹,Bhattarai Bijay¹^ORCID,Kaplan Will¹,Li Zhongzheng²,Curtis Long Marcus John³,Aye Yimon⁴³,Nagorny Pavel¹^ORCID

Affiliation:

1. Chemistry Department, University of Michigan, Ann Arbor, Michigan 48109, United States

2. Department of Chemistry, Nankai University, Nankai 300071, People’s Republic of China

3. Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States

4. Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland

Funder

Office of Naval Research

Arnold and Mabel Beckman Foundation

?cole Polytechnique F?d?rale de Lausanne

Novartis Foundation

National Institute of General Medical Sciences

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Division of Chemistry

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.8b12870

Reference97 articles.

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3. bAhmad, V. U.; Basha, A. Spectroscopic Data of Steroid Glycosides: Cardenolides and Pregnanes; Springer: New York, 2006; Chapter 4, pp 2089–2759.

4. The digitalis-like steroid hormones: New mechanisms of action and biological significance

5. Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

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