Chemical Synthesis Enables Structural Reengineering of Aglaroxin C Leading to Inhibition Bias for Hepatitis C Viral Infection

Author:

Zhang Wenhan1,Liu Shufeng2,Maiga Rayelle I.,Pelletier Jerry,Brown Lauren E.1ORCID,Wang Tony T.2,Porco John A.1ORCID

Affiliation:

1. Department of Chemistry, Center for Molecular Discovery (BU-CMD), Boston University, Boston, Massachusetts 02215, United States

2. Laboratory of Vector-Borne Viral Diseases, Division of Viral Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20903, United States

Funder

Canadian Institutes of Health Research

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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