Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The “Undoing” of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network-Reference-Cited by-同舟云学术

Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The “Undoing” of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network

Published:2019-01-15 Issue:4 Volume:141 Page:1555-1567
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Hu Shenshen,Offenbacher Adam R.¹,Thompson Erin M.²,Gee Christine L.,Wilcoxen Jarett³^ORCID,Carr Cody A. M.^ORCID,Prigozhin Daniil M.,Yang Vanessa,Alber Tom,Britt R. David³^ORCID,Fraser James S.²,Klinman Judith P.^ORCID

Affiliation:

1. Department of Chemistry, East Carolina University, Greenville, North Carolina 27858, United States

2. Department of Bioengineering and Therapeutic Science, University of California, San Francisco, San Francisco, California 94158, United States

3. Department of Chemistry, University of California, Davis, Davis, California 95695, United States

Funder

Howard Hughes Medical Institute

David and Lucile Packard Foundation

National Institute of General Medical Sciences

National Science Foundation

Office of the President, University of California

Publisher

American Chemical Society (ACS)