Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

Author:

Zong Guanghui1ORCID,Hu Zhijian,O’Keefe Sarah2,Tranter Dale34,Iannotti Michael J.5ORCID,Baron Ludivine67,Hall Belinda8,Corfield Katherine8,Paatero Anja O.34,Henderson Mark J.5,Roboti Peristera2,Zhou Jianhong,Sun Xianwei9,Govindarajan Mugunthan10,Rohde Jason M.5,Blanchard Nicolas11ORCID,Simmonds Rachel8,Inglese James5ORCID,Du Yuchun,Demangel Caroline67,High Stephen2,Paavilainen Ville O.34ORCID,Shi Wei Q.12ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States

2. School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, United Kingdom

3. University of Helsinki, HiLIFE, Helsinki, Finland

4. Institute of Biotechnology, Helsinki, Finland

5. National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States

6. Immunobiology of Infection Unit, Institut Pasteur, 75015 Paris, France

7. INSERM, U1221, 75005 Paris, France

8. Department of Microbial Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom

9. Department of Radiology, Baylor College of Medicine, Houston, Texas 77030, United States

10. Emory Institute for Drug Development, Emory University, 954 Gatewood Road, Atlanta, Georgia 30329, United States

11. Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA, UMR 7042, 68000 Mulhouse, France

12. Department of Chemistry, Ball State University, Muncie, Indiana 47306, United States

Funder

National Center for Advancing Translational Sciences

Sigrid Jus?liuksen S??ti?

University of Arkansas

Institut National de la Sant? et de la Recherche M?dicale

Arkansas Biosciences Institute

Wellcome Trust

Suomen Akatemia

Institut Pasteur

National Institute of General Medical Sciences

Fondation Raoul Follereau

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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