Mechanistic Study of the sPLA2-Mediated Hydrolysis of a Thio-ester Pro Anticancer Ether Lipid-Reference-Cited by-同舟云学术

Mechanistic Study of the sPLA2-Mediated Hydrolysis of a Thio-ester Pro Anticancer Ether Lipid

Published:2009-08-07 Issue:34 Volume:131 Page:12193-12200
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Linderoth Lars¹,Fristrup Peter¹,Hansen Martin¹,Melander Fredrik¹,Madsen Robert¹,Andresen Thomas L.¹,Peters Günther H.¹

Affiliation:

1. Department of Chemistry, MEMPHYS-Center for Biomembrane Physics, Technical University of Denmark, DK-2800 Kgs. Lyngby Denmark, Department of Chemistry, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark, Materials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, California 91125, LiPlasome Pharma A/S, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark, and DTU Nanotech, Technical University of Denmark, DK-4000 Roskilde, Denmark

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja901412j

Reference38 articles.

1. Secretory Phospholipase A2

2. The expanding superfamily of phospholipase A2 enzymes: classification and characterization

3. Phospholipase A2 expression in tumours: a target for therapeutic intervention?

4. Synthesis and Biological Activity of Anticancer Ether Lipids That Are Specifically Released by Phospholipase A2 in Tumor Tissue

5. Advanced strategies in liposomal cancer therapy: Problems and prospects of active and tumor specific drug release

Cited by 60 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enzyme-responsive liposomes for controlled drug release;Drug Discovery Today;2024-07

2. Prodrugs: A Novel Approach of Drug Delivery;International Journal of Pharmacy and Chemistry;2024-06-29

3. Tumor selective self-assembled nanomicelles of carbohydrate-epothilone B conjugate for targeted chemotherapy;European Journal of Medicinal Chemistry;2023-11

4. Candida antarctica lipase B performance in organic solvent at varying water activities studied by molecular dynamics simulations;Computational and Structural Biotechnology Journal;2023

5. Rational design of phospholipase-sensitive intelligent liposomal nanocarriers for prodrug and drug delivery in cancer therapy;Phospholipases in Physiology and Pathology;2023