Phospholipidosis as a Function of Basicity, Lipophilicity, and Volume of Distribution of Compounds
Author:
Affiliation:
1. Departments of Discovery Toxicology, Discovery Analytical Sciences, Discovery Chemistry, and Bioinformatics, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, Connecticut 06492
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx9003825
Reference74 articles.
1. Drug-Induced Phospholipidosis: Are There Functional Consequences?
2. Drug-induced phospholipidosis: issues and future directions
3. In Vitro Detection of Drug-Induced Phospholipidosis Using Gene Expression and Fluorescent Phospholipid Based Methodologies
4. Evaluation of a Published in Silico Model and Construction of a Novel Bayesian Model for Predicting Phospholipidosis Inducing Potential
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