Identification of 2-Amino-1,7-dimethylimidazo[4,5-g]quinoxaline: An Abundant Mutagenic Heterocyclic Aromatic Amine Formed in Cooked Beef-Reference-Cited by-同舟云学术

Identification of 2-Amino-1,7-dimethylimidazo[4,5-g]quinoxaline: An Abundant Mutagenic Heterocyclic Aromatic Amine Formed in Cooked Beef

Published:2007-02-23 Issue:3 Volume:20 Page:520-530
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Turesky Robert J.¹,Goodenough Angela K.¹,Ni Weijuan¹,McNaughton Lynn¹,LeMaster David M.¹,Holland Ricky D.¹,Wu Rebekah W.¹,Felton James S.¹

Affiliation:

1. Division of Environmental Disease Prevention and Division of Molecular Medicine, New York State Department of Health, Albany, New York 12201, Division of System Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas 72079, and Chemistry, Materials and Life Sciences Directorate, P.O. Box 808, Lawrence Livermore National, Laboratory, Livermore, California 94551

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx600317r

Reference46 articles.

2. Lang, N. P., Butler, M. A., Massengill, J. P., Lawson, M., Stotts, R. C., Hauer-Jensen, M., and Kadlubar, F. F. (1994) Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.Cancer Epidemiol. Biomarkers Prev.3, 675−682.

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Imidazoquinoxaline as a Privileged Fused Pharmacophore in Anticancer Drug Development: A Review of Synthetic Strategies and Medicinal Aspects;ChemistrySelect;2022-10-04

2. Dietary meat mutagens intake and cancer risk: A systematic review and meta-analysis;Frontiers in Nutrition;2022-09-23

3. Heterocyclic amines in cooked meat products, shortcomings during evaluation, factors influencing formation, risk assessment and mitigation strategies;Meat Science;2022-02

4. Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta;Genes and Environment;2021-09-16

5. Metabolism and biomarkers of heterocyclic aromatic amines in humans;Genes and Environment;2021-07-16