Stereoselective Synthesis of 3,3-Diarylacrylonitriles as Tubulin Polymerization Inhibitors-Reference-Cited by-同舟云学术

Stereoselective Synthesis of 3,3-Diarylacrylonitriles as Tubulin Polymerization Inhibitors

Published:2008-05-01 Issue:11 Volume:73 Page:4241-4244
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Fang Zhenglai¹,Song Yunlong¹,Sarkar Taradas¹,Hamel Ernest¹,Fogler William E.¹,Agoston Gregory E.¹,Fanwick Phillip E.¹,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences, and the Purdue Cancer Center, Purdue University, West Lafayette, Indiana 47907, Toxicology and Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, EntreMed, Inc., Rockville, Maryland 20850, and Department of Chemistry, Purdue University, West Lafayette...

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo800428b

Reference41 articles.

1. Tubulin and microtubule structure

2. Recent advances in the field of tubulin polymerization inhibitors

3. Natural, semisynthetic and synthetic microtubule inhibitors for cancer therapy

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