An Automated Multicycle Immunoaffinity Enrichment Approach Developed for Sensitive Mouse IgG1 Antibody Drug Analysis in Mouse Plasma Using LC/MS/MS-Reference-Cited by-同舟云学术

An Automated Multicycle Immunoaffinity Enrichment Approach Developed for Sensitive Mouse IgG1 Antibody Drug Analysis in Mouse Plasma Using LC/MS/MS

Published:2021-04-13 Issue:16 Volume:93 Page:6348-6354
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Dong Linlin¹^ORCID,Bebrin Nicole¹,Piatkov Konstantin¹,Abdul-Hadi Kojo¹,Iwasaki Shinji¹,Qian Mark G.¹,Wei Dong¹

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International, Inc., 35 Landsdowne Street, Cambridge, Massachusetts 02139, United States

Funder

Takeda Pharmaceuticals International, Inc.

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c00698

Reference21 articles.

1. Next generation antibody drugs: pursuit of the 'high-hanging fruit'

2. Developments and Challenges for mAb-Based Therapeutics

3. Pharmacokinetic Variability of Therapeutic Antibodies in Humans: A Comprehensive Review of Population Pharmacokinetic Modeling Publications

4. Pharmacokinetic/pharmacodynamic relationship of therapeutic monoclonal antibodies used in oncology: Part 1, monoclonal antibodies, antibody-drug conjugates and bispecific T-cell engagers

5. The immunogenicity of humanized and fully human antibodies

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