Sensing an Oxygen Sensor: Development and Application of Activity-Based Assays Directly Monitoring HIF Heterodimerization-Reference-Cited by-同舟云学术

Sensing an Oxygen Sensor: Development and Application of Activity-Based Assays Directly Monitoring HIF Heterodimerization

Published:2021-10-22 Issue:43 Volume:93 Page:14462-14470
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Janssens Liesl K.¹,Stove Christophe P.¹^ORCID

Affiliation:

1. Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium

Funder

Partnership for Clean Competition

Bijzonder Onderzoeksfonds

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c02923

Reference32 articles.

1. Hypoxia-Inducible Factors in Physiology and Medicine

2. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

3. Transcriptional regulation by hypoxia inducible factors

4. Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG–EGFR/ErbB4 autocrine loop

5. Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

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