Physicochemical and Functional Characterization of Differential CRISPR-Cas9 Ribonucleoprotein Complexes
Author:
Affiliation:
1. Cell Therapy Engineering and Development, Genentech, 1 DNA Way, South San Francisco, California 94080, United States
2. Protein Analytical Chemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c04795
Reference39 articles.
1. Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2. CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future
3. CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms
4. Protospacer recognition motifs
5. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
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