Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Therapeutic Antibody Cocktail REGEN-COV Concentrations in COVID-19 Patient Serum
Author:
Funder
Regeneron Pharmaceuticals
U.S. Department of Health and Human Services
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c01613
Reference13 articles.
1. Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
2. REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters
3. REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19
4. Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies
5. Bioanalytical LC–MS/MS of protein-based biopharmaceuticals
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