Intracellular Drug Uptake—A Comparison of Single Cell Measurements Using ToF-SIMS Imaging and Quantification from Cell Populations with LC/MS/MS-Reference-Cited by-同舟云学术

Intracellular Drug Uptake—A Comparison of Single Cell Measurements Using ToF-SIMS Imaging and Quantification from Cell Populations with LC/MS/MS

Published:2017-11-08 Issue:22 Volume:89 Page:11944-11953
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Newman Carla F.¹²^ORCID,Havelund Rasmus³^ORCID,Passarelli Melissa K.³,Marshall Peter S.¹,Francis Ian¹,West Andy¹,Alexander Morgan R.²,Gilmore Ian S.³,Dollery Colin T.¹

Affiliation:

1. GlaxoSmithKline, Stevenage SG1 2NY, United Kingdom

2. Division of Advanced Materials and Healthcare Technologies, School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom

3. National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL), Teddington, Middlesex TW11 0LW, United Kingdom

Funder

GlaxoSmithKline

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.7b01436

Reference50 articles.

1. Drug discovery in pharmaceutical industry: productivity challenges and trends

2. Intracellular Drug Concentrations

3. Lost in Translation (LiT): IUPHAR Review 6