Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry-Reference-Cited by-同舟云学术

Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry

Published:2017-05-25 Issue:12 Volume:89 Page:6821-6826
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Husser Christophe¹,Brink Andreas¹,Zell Manfred¹,Müller Martina B.¹,Koller Erich¹,Schadt Simone¹^ORCID

Affiliation:

1. Roche Pharma Research and Early Development, Roche Innovation Center Basel, Grenzacherstr. 124, CH-4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.7b01244

Reference25 articles.

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2. Oligonucleotide Therapies: The Past and the Present

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4. Delivery materials for siRNA therapeutics

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