Flow-through Capture and in Situ Amplification Can Enable Rapid Detection of a Few Single Molecules of Nucleic Acids from Several Milliliters of Solution-Reference-Cited by-同舟云学术

Flow-through Capture and in Situ Amplification Can Enable Rapid Detection of a Few Single Molecules of Nucleic Acids from Several Milliliters of Solution

Published:2016-07-18 Issue:15 Volume:88 Page:7647-7653
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Schlappi Travis S.¹,McCalla Stephanie E.¹,Schoepp Nathan G.¹,Ismagilov Rustem F.¹

Affiliation:

1. Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, United States

Funder

Defense Advanced Research Projects Agency

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.analchem.6b01485

Reference48 articles.

1. Routine nucleic acid testing of blood donations fails to detect all human immunodeficiency virus-positive blood donors

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3. Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

4. Suppression of plasma viral load below 20 copies/ml is required to achieve a long-term response to therapy

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