Generic Hybrid Ligand Binding Assay Liquid Chromatography High-Resolution Mass Spectrometry-Based Workflow for Multiplexed Human Immunoglobulin G1 Quantification at the Intact Protein Level: Application to Preclinical Pharmacokinetic Studies-Reference-Cited by-同舟云学术

Generic Hybrid Ligand Binding Assay Liquid Chromatography High-Resolution Mass Spectrometry-Based Workflow for Multiplexed Human Immunoglobulin G1 Quantification at the Intact Protein Level: Application to Preclinical Pharmacokinetic Studies

Published:2017-02-09 Issue:4 Volume:89 Page:2628-2635
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Lanshoeft Christian¹²^ORCID,Cianférani Sarah²,Heudi Olivier¹

Affiliation:

1. Novartis Institutes for Biomedical Research, Drug Metabolism and Pharmacokinetics, Novartis Campus, 4056 Basel, Switzerland

2. Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000 Strasbourg, France

Funder

Novartis Pharma

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.6b04997

Reference34 articles.

1. Infliximab quantitation in human plasma by liquid chromatography-tandem mass spectrometry: towards a standardization of the methods?

2. Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry

3. Bioanalytical LC–MS/MS of protein-based biopharmaceuticals

4. Application and challenges in using LC–MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery

5. LC-MS/MS Validation Analysis of Trastuzumab Using dSIL Approach for Evaluating Pharmacokinetics

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