Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis-Reference-Cited by-同舟云学术

Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis

Published:2017-02-09 Issue:4 Volume:89 Page:2250-2258
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Li Jing¹,Wei Hui²,Krystek Stanley R.³,Bond Derek⁴,Brender Ty M.⁵,Cohen Daniel⁶,Feiner Jena⁷,Hamacher Nels³,Harshman Johanna³,Huang Richard Y.-C.⁸,Julien Susan H.⁹,Lin Zheng⁶,Moore Kristina⁶,Mueller Luciano⁸,Noriega Claire⁹,Sejwal Preeti⁸,Sheppard Paul⁹,Stevens Brenda⁹,Chen Guodong⁸,Tymiak Adrienne A.⁸,Gross Michael L.¹^ORCID,Schneeweis Lumelle A.⁶^ORCID

Affiliation:

1. Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130-4889, United States

2. Biologics Development, Bristol-Myers Squibb, 311 Pennington-Rocky Hill Road, Pennington, New Jersey 08534, United States

3. Molecular Structure & Design, Bristol-Myers Squibb, Rt. 206 & Province Line Rd., Princeton, New Jersey 08543, United States

4. Process Development, Bristol-Myers Squibb, 1201 Eastlake Ave E., Seattle Washington 98102, United States

5. Discovery Biology, Bristol-Myers Squibb, 1201 Eastlake Ave E., Seattle Washington 98102, United States

6. Protein Science, Bristol-Myers Squibb, Rt. 206 & Province Line Rd., Princeton, New Jersey 08543, United States

7. Applied Genomics, Bristol-Myers Squibb, 311 Pennington-Rocky Hill Road, Pennington, New Jersey 08534, United States

8. Bioanalytical and Discovery Analytical Sciences, Research and Development, Bristol-Myers Squibb, Rt. 206 & Province Line Rd., Princeton, New Jersey 08543, United States

9. Protein Engineering, Bristol-Myers Squibb, 1201 Eastlake Ave E., Seattle Washington 98102, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.6b03058

Reference61 articles.

1. Characterization of Therapeutic Antibodies and Related Products

2. High Throughput T Epitope Mapping and Vaccine Development