Integrated Thermal Proteome Profiling and Affinity Ultrafiltration Mass Spectrometry (iTPAUMS): A Novel Paradigm for Elucidating the Mechanism of Action of Natural Products-Reference-Cited by-同舟云学术

Integrated Thermal Proteome Profiling and Affinity Ultrafiltration Mass Spectrometry (iTPAUMS): A Novel Paradigm for Elucidating the Mechanism of Action of Natural Products

Published:2024-09-10 Issue: Volume: Page:
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Yu Hengyuan¹,Chen Yang²,Wang Yichen¹,Fu Weiliang¹,Xu Rui¹,Liu Jie¹³⁴,Chen Yong¹⁵,Liu Xuesong¹⁵,Wu Yongjiang¹^ORCID,Xu Tengfei¹⁵^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. Department of Clinical Pharmacy, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, Xihu University School of Medicine, Hangzhou 310006, China

3. Shandong C.P. Freda Pharmaceutical Co., Ltd., Jinan 250104, China

4. Engineering Research Center for Medicines of Orthopedic Pain of Shandong Province, Jinan 250104, China

5. Cangnan County Qiushi Innovation Research Institute of Traditional Chinese Medicine, Wenzhou 325800, China

Funder

National Natural Science Foundation of China

Health Science and Technology Project of Hangzhou Municipal Health Commission

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.4c03398

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4. Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase

5. CETSA and thermal proteome profiling strategies for target identification and drug discovery of natural products